Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 14 Researches
7.6
USERS' SCORE
Good
Based on 6 Reviews
8.2
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Lutein (Free Lutein)(From Lutein Esters)(From Marigold Flowers Extract) (Tagetes erecta)
20 mg
*
Top Medical Research Studies
8
Lutein shows promise for heart health
We examined the potential of lutein to protect against heart damage caused by myocardial infarction, using a model induced by isoprenaline. The study showed that pretreating rats with lutein significantly reduced heart injury markers and improved heart function compared to untreated individuals.
Notably, lutein not only decreased damaged heart cells but also positively influenced several protective pathways at the molecular level. However, while the results are promising, they indicate that further research is necessary to fully understand lutein's role in heart health.
Notably, lutein not only decreased damaged heart cells but also positively influenced several protective pathways at the molecular level. However, while the results are promising, they indicate that further research is necessary to fully understand lutein's role in heart health.
Read More
9
Lutein shows potential heart benefits
We explored the heart-protective effects of lutein in a study using a rat model of heart failure induced by isoproterenol.
Healthy male rats were divided into four groups receiving different treatments, including lutein.
Results showed that lutein significantly reduced heart damage and inflammation markers while boosting antioxidant defenses. It also improved heart tissue structure. While the findings are promising, further research is needed to confirm lutein's benefits in human heart disease.
Healthy male rats were divided into four groups receiving different treatments, including lutein.
Results showed that lutein significantly reduced heart damage and inflammation markers while boosting antioxidant defenses. It also improved heart tissue structure. While the findings are promising, further research is needed to confirm lutein's benefits in human heart disease.
Read More
8
We examined how lutein, a powerful antioxidant, could potentially protect the heart from damage during ischemia-reperfusion injury. By developing a specialized delivery system for lutein, we injected it into rats to see if it could improve mitochondrial function.
Our findings suggested that the antioxidant properties of lutein helped restore mitochondrial health and reduce cell death in heart tissues. However, while we observed promising results regarding mitochondrial function, the overall benefit of lutein treatment on heart disease requires further investigation to fully understand its effectiveness.
Our findings suggested that the antioxidant properties of lutein helped restore mitochondrial health and reduce cell death in heart tissues. However, while we observed promising results regarding mitochondrial function, the overall benefit of lutein treatment on heart disease requires further investigation to fully understand its effectiveness.
Read More
Most Useful Reviews
7
Reduces heart disease
3 people found this helpful
Lutein is excellent! The quality is commendable, and I will repurchase if necessary. It enhances "dark adaptability," filters blue light, and improves "visual adaptability" and "recognition function." It also aids in preventing "macular degeneration," lowers the risk of "cataracts," alleviates "visual fatigue," and protects the "crystals" of the eyes. Furthermore, it aids in preventing the "sequelae of high myopia," reduces the incidence of "glaucoma," improves "brain health and cognitive function," and helps prevent "cardiovascular" and "metabolic diseases."
Read More
9
Prevents heart disease
Lutein is a potent antioxidant with numerous health benefits, particularly for eye health. It protects the eyes from free radical and UV damage, thereby reducing the risk of vision deterioration. Additionally, lutein enhances contrast perception and night vision while preventing eye diseases like cataracts and macular degeneration. Its benefits extend to skin health, minimising damage from UV rays and oxidative stress, contributing further to overall wellbeing.
Read More
9
Supports heart disease
I'm repurchasing for the second time, and it has genuinely improved my eyesight, particularly with eye diseases! I will continue to take it.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 14 Researches
7.6
- All Researches
9
Innovative lutein delivery for heart health
We investigated a new method of delivering lutein, a potential treatment for hypertensive heart disease. Using biomimetic nanoparticles cloaked in macrophage membranes, we analyzed their ability to target and treat cardiac fibrosis in a specific model.
Our results showed that these nanoparticles not only improved heart function but also reduced fibrosis effectively. Notably, they did this without causing any harmful side effects. Overall, this innovative delivery system could make lutein a more viable option for managing heart diseases linked to pressure overload.
Our results showed that these nanoparticles not only improved heart function but also reduced fibrosis effectively. Notably, they did this without causing any harmful side effects. Overall, this innovative delivery system could make lutein a more viable option for managing heart diseases linked to pressure overload.
Read More
9
Lutein shows potential heart benefits
We explored the heart-protective effects of lutein in a study using a rat model of heart failure induced by isoproterenol.
Healthy male rats were divided into four groups receiving different treatments, including lutein.
Results showed that lutein significantly reduced heart damage and inflammation markers while boosting antioxidant defenses. It also improved heart tissue structure. While the findings are promising, further research is needed to confirm lutein's benefits in human heart disease.
Healthy male rats were divided into four groups receiving different treatments, including lutein.
Results showed that lutein significantly reduced heart damage and inflammation markers while boosting antioxidant defenses. It also improved heart tissue structure. While the findings are promising, further research is needed to confirm lutein's benefits in human heart disease.
Read More
8
We examined the connection between serum carotenoid levels, including lutein, and cardiovascular-kidney-metabolic syndrome in a diverse group of adult participants. Analyzing data from the NHANES 2017-2018, we discovered that higher serum levels of lutein/zeaxanthin corresponded with a reduced risk of advanced CKM syndrome. In fact, those in the highest quartile for lutein showed a significant odds ratio of 0.26, indicating a strong inverse relationship with disease prevalence.
Overall, our findings suggest that increasing carotenoid levels might contribute to better heart health.
Overall, our findings suggest that increasing carotenoid levels might contribute to better heart health.
Read More
8
We examined how lutein, a powerful antioxidant, could potentially protect the heart from damage during ischemia-reperfusion injury. By developing a specialized delivery system for lutein, we injected it into rats to see if it could improve mitochondrial function.
Our findings suggested that the antioxidant properties of lutein helped restore mitochondrial health and reduce cell death in heart tissues. However, while we observed promising results regarding mitochondrial function, the overall benefit of lutein treatment on heart disease requires further investigation to fully understand its effectiveness.
Our findings suggested that the antioxidant properties of lutein helped restore mitochondrial health and reduce cell death in heart tissues. However, while we observed promising results regarding mitochondrial function, the overall benefit of lutein treatment on heart disease requires further investigation to fully understand its effectiveness.
Read More
8
In examining the relationship between serum carotenoids, including lutein, and cardiovascular disease (CVD), we analyzed data from over 12,000 adults in the U.S. from the NHANES survey. Our findings revealed that higher levels of carotenoids, particularly lutein, were linked to a lower risk of heart disease.
Specifically, lutein was noted to significantly reduce the prevalence of heart attacks and stroke. This suggests that increasing our intake of carotenoid-rich foods might help in preventing heart-related issues.
Specifically, lutein was noted to significantly reduce the prevalence of heart attacks and stroke. This suggests that increasing our intake of carotenoid-rich foods might help in preventing heart-related issues.
Read More
User Reviews
USERS' SCORE
Good
Based on 6 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
7
Reduces heart disease
3 people found this helpful
Lutein is excellent! The quality is commendable, and I will repurchase if necessary. It enhances "dark adaptability," filters blue light, and improves "visual adaptability" and "recognition function." It also aids in preventing "macular degeneration," lowers the risk of "cataracts," alleviates "visual fatigue," and protects the "crystals" of the eyes. Furthermore, it aids in preventing the "sequelae of high myopia," reduces the incidence of "glaucoma," improves "brain health and cognitive function," and helps prevent "cardiovascular" and "metabolic diseases."
Read More
9
Prevents heart disease
Lutein is a potent antioxidant with numerous health benefits, particularly for eye health. It protects the eyes from free radical and UV damage, thereby reducing the risk of vision deterioration. Additionally, lutein enhances contrast perception and night vision while preventing eye diseases like cataracts and macular degeneration. Its benefits extend to skin health, minimising damage from UV rays and oxidative stress, contributing further to overall wellbeing.
Read More
9
Supports heart disease
I'm repurchasing for the second time, and it has genuinely improved my eyesight, particularly with eye diseases! I will continue to take it.
Read More
9
Treats heart disease
2 people found this helpful
Since then, my dry eye condition has vanished.
Read More
7.5
Protects from heart disease
2 people found this helpful
Excellent! As I age, I've noticed presbyopia. I purchased this because my eyes seemed dull lately. Lutein and Zeaxanthin, essential for over 90% of vision, absorb ultraviolet and blue light to safeguard against various eye diseases. The prevalence of screen use today exposes eyes to harmful blue light, possibly leading to presbyopia and conditions like macular degeneration and cataracts. Taking lutein can help maintain the density of macular pigment and protect my eyes from such diseases and presbyopia.
Read More
Frequently Asked Questions
7
Reduces heart disease
3 people found this helpful
Lutein is excellent! The quality is commendable, and I will repurchase if necessary. It enhances "dark adaptability," filters blue light, and improves "visual adaptability" and "recognition function." It also aids in preventing "macular degeneration," lowers the risk of "cataracts," alleviates "visual fatigue," and protects the "crystals" of the eyes. Furthermore, it aids in preventing the "sequelae of high myopia," reduces the incidence of "glaucoma," improves "brain health and cognitive function," and helps prevent "cardiovascular" and "metabolic diseases."
9
Treats heart disease
2 people found this helpful
Since then, my dry eye condition has vanished.
9
Prevents heart disease
Lutein is a potent antioxidant with numerous health benefits, particularly for eye health. It protects the eyes from free radical and UV damage, thereby reducing the risk of vision deterioration. Additionally, lutein enhances contrast perception and night vision while preventing eye diseases like cataracts and macular degeneration. Its benefits extend to skin health, minimising damage from UV rays and oxidative stress, contributing further to overall wellbeing.
4
Aids heart disease
The potential benefits of lutein include preventing age-related macular degeneration, reducing cataract incidence, enhancing visual contrast sensitivity for diabetic retinopathy patients, boosting cognitive function and memory, decreasing carotid artery intima-media thickness, and even preventing cardiovascular disease while lowering cancer risks.
8
In examining the relationship between serum carotenoids, including lutein, and cardiovascular disease (CVD), we analyzed data from over 12,000 adults in the U.S. from the NHANES survey. Our findings revealed that higher levels of carotenoids, particularly lutein, were linked to a lower risk of heart disease.
Specifically, lutein was noted to significantly reduce the prevalence of heart attacks and stroke. This suggests that increasing our intake of carotenoid-rich foods might help in preventing heart-related issues.
Specifically, lutein was noted to significantly reduce the prevalence of heart attacks and stroke. This suggests that increasing our intake of carotenoid-rich foods might help in preventing heart-related issues.
8
We examined how lutein, a powerful antioxidant, could potentially protect the heart from damage during ischemia-reperfusion injury. By developing a specialized delivery system for lutein, we injected it into rats to see if it could improve mitochondrial function.
Our findings suggested that the antioxidant properties of lutein helped restore mitochondrial health and reduce cell death in heart tissues. However, while we observed promising results regarding mitochondrial function, the overall benefit of lutein treatment on heart disease requires further investigation to fully understand its effectiveness.
Our findings suggested that the antioxidant properties of lutein helped restore mitochondrial health and reduce cell death in heart tissues. However, while we observed promising results regarding mitochondrial function, the overall benefit of lutein treatment on heart disease requires further investigation to fully understand its effectiveness.
8
We examined the effects of lutein on heart disease, specifically its role in mitigating cardiac remodeling linked to angiotensin II, a key player in heart failure. In laboratory settings, lutein significantly reduced harmful collagen expression in heart cells and curtailed superoxide generation and inflammation. Mice treated with lutein exhibited less cardiac remodeling compared to untreated ones. The protective effect of lutein appears to stem from its ability to suppress interleukin-11, a problematic protein in this process. Overall, while promising, the effects need further validation in clinical settings.
9
Lutein shows potential heart benefits
We explored the heart-protective effects of lutein in a study using a rat model of heart failure induced by isoproterenol.
Healthy male rats were divided into four groups receiving different treatments, including lutein.
Results showed that lutein significantly reduced heart damage and inflammation markers while boosting antioxidant defenses. It also improved heart tissue structure. While the findings are promising, further research is needed to confirm lutein's benefits in human heart disease.
Healthy male rats were divided into four groups receiving different treatments, including lutein.
Results showed that lutein significantly reduced heart damage and inflammation markers while boosting antioxidant defenses. It also improved heart tissue structure. While the findings are promising, further research is needed to confirm lutein's benefits in human heart disease.
7
We examined how lutein, a carotenoid known for its antioxidant properties, impacts inflammation in those with coronary artery disease (CAD). Our study involved measuring levels of lutein and other carotenoids in blood samples from CAD patients.
Further, we tested the anti-inflammatory effects of lutein on blood cells from these patients. We found that higher lutein levels were linked to lower inflammation markers. Overall, our results suggest that lutein might help reduce chronic inflammation associated with CAD.
Further, we tested the anti-inflammatory effects of lutein on blood cells from these patients. We found that higher lutein levels were linked to lower inflammation markers. Overall, our results suggest that lutein might help reduce chronic inflammation associated with CAD.
7
We conducted a systematic review and meta-analysis to assess how lutein impacts cardiometabolic health throughout different life stages. Our research included 71 studies with over 387,000 participants.
We found that higher levels of lutein in the diet and bloodstream were linked to a reduced risk of heart disease and stroke. However, there was no notable impact on type 2 diabetes. While lutein showed promise for overall heart health, especially concerning metabolic syndrome, the lack of large intervention studies, particularly in children and pregnant women, leaves some unanswered questions.
We found that higher levels of lutein in the diet and bloodstream were linked to a reduced risk of heart disease and stroke. However, there was no notable impact on type 2 diabetes. While lutein showed promise for overall heart health, especially concerning metabolic syndrome, the lack of large intervention studies, particularly in children and pregnant women, leaves some unanswered questions.
References
- Chen M, Cai S, Jia Q, Suo Y, Tang Y, et al. Inverse Relationship Between Serum Carotenoid Levels and Cardiovascular-Kidney-Metabolic Syndrome Among the General Adult Population. J Diabetes. 2025;17:e70046. doi:10.1111/1753-0407.70046
- Gür FM, Bilgiç S, Aktaş İ. Lutein, a non-provitamin A carotenoid, reduces cisplatin-induced cardiotoxicity. Prostaglandins Other Lipid Mediat. 2025;177:106965. doi:10.1016/j.prostaglandins.2025.106965
- Shi P, Sha Y, Wang X, Yang T, Wu J, et al. Targeted Delivery and ROS-Responsive Release of Lutein Nanoassemblies Inhibit Myocardial Ischemia-Reperfusion Injury by Improving Mitochondrial Function. Int J Nanomedicine. 2024;19:11973. doi:10.2147/IJN.S488532
- Masle AM, Kibel A, Jukić I, Čičak P, Selthofer-Relatić K, et al. Enhancing Endothelial Function with Nutrient-Enriched Table Hen Eggs: A Randomized Study in Patients Recovering from Acute Coronary Syndrome. Clin Interv Aging. 2024;19:953. doi:10.2147/CIA.S461821
- Liu Y, Yang G, Huo S, Wu J, Ren P, et al. Lutein suppresses ferroptosis of cardiac microvascular endothelial cells via positive regulation of IRF in cardiac hypertrophy. Eur J Pharmacol. 2023;959:176081. doi:10.1016/j.ejphar.2023.176081
- Guo T, Chen L, Li F, Cao Y, Li D, et al. Biomimetic nanoparticles loaded lutein functionalized by macrophage membrane for targeted amelioration pressure overload-induced cardiac fibrosis. Biomed Pharmacother. 2023;167:115579. doi:10.1016/j.biopha.2023.115579
- Wang M, Tang R, Zhou R, Qian Y, Di D. The protective effect of serum carotenoids on cardiovascular disease: a cross-sectional study from the general US adult population. Front Nutr. 2023;10:1154239. doi:10.3389/fnut.2023.1154239
- Abdelmonem M, Ibrahim SM, Essam RM, Amin HAA, Abd-Elmawla MA. Lutein exerts its cardioprotective effect against the experimental model of isoprenaline-induced myocardial infarction via MIAT/miR-200a/Nrf2/TXINP pathway. J Biochem Mol Toxicol. 2021;35:e22899. doi:10.1002/jbt.22899
- Chen Y, Wang L, Huang S, Ke J, Wang Q, et al. Lutein attenuates angiotensin II- induced cardiac remodeling by inhibiting AP-1/IL-11 signaling. Redox Biol. 2021;44:102020. doi:10.1016/j.redox.2021.102020
- Li N, Wu X, Zhuang W, Xia L, Chen Y, et al. Green leafy vegetable and lutein intake and multiple health outcomes. Food Chem. 2021;360:130145. doi:10.1016/j.foodchem.2021.130145
- Wang L, Tao L, Hao L, Stanley TH, Huang KH, et al. A Moderate-Fat Diet with One Avocado per Day Increases Plasma Antioxidants and Decreases the Oxidation of Small, Dense LDL in Adults with Overweight and Obesity: A Randomized Controlled Trial. J Nutr. 2020;150:276. doi:10.1093/jn/nxz231
- Ouyang B, Li Z, Ji X, Huang J, Zhang H, et al. The protective role of lutein on isoproterenol-induced cardiac failure rat model through improving cardiac morphology, antioxidant status via positively regulating Nrf2/HO-1 signalling pathway. Pharm Biol. 2019;57:529. doi:10.1080/13880209.2019.1649436
- Chung RWS, Leanderson P, Lundberg AK, Jonasson L. Lutein exerts anti-inflammatory effects in patients with coronary artery disease. Atherosclerosis. 2017;262:87. doi:10.1016/j.atherosclerosis.2017.05.008
- Leermakers ET, Darweesh SK, Baena CP, Moreira EM, Melo van Lent D, et al. The effects of lutein on cardiometabolic health across the life course: a systematic review and meta-analysis. Am J Clin Nutr. 2016;103:481. doi:10.3945/ajcn.115.120931
